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Another supervolcano in California is not as dormant as we thought

Genetically modified organisms (GMO) - чт, 2018-08-09 13:09
The Long Valley Caldera in east California unleashed a supervolcano eruption 760,000 years ago. Today it is quiet but it may have a few smaller eruptions left in it
Категории: Science and society

Another supervolcano in California is not as dormant as we thought

HIV and AIDS - чт, 2018-08-09 13:09
The Long Valley Caldera in east California unleashed a supervolcano eruption 760,000 years ago. Today it is quiet but it may have a few smaller eruptions left in it
Категории: Healthcare, Science and society

Another supervolcano in California is not as dormant as we thought

Genetics - чт, 2018-08-09 13:09
The Long Valley Caldera in east California unleashed a supervolcano eruption 760,000 years ago. Today it is quiet but it may have a few smaller eruptions left in it
Категории: Biology

Tight underwear really is linked to lower sperm counts in men

Genetics - чт, 2018-08-09 01:00
Men who wear boxer shorts have higher sperm levels than men who wear tight underwear, although the difference shouldn't usually be enough to affect fertility
Категории: Biology

Tight underwear really is linked to lower sperm counts in men

HIV and AIDS - чт, 2018-08-09 01:00
Men who wear boxer shorts have higher sperm levels than men who wear tight underwear, although the difference shouldn't usually be enough to affect fertility
Категории: Healthcare, Science and society

Tight underwear really is linked to lower sperm counts in men

Genetically modified organisms (GMO) - чт, 2018-08-09 01:00
Men who wear boxer shorts have higher sperm levels than men who wear tight underwear, although the difference shouldn't usually be enough to affect fertility
Категории: Science and society

Inducing labour at 39 weeks leads to fewer emergency Caesareans

Genetics - чт, 2018-08-09 00:00
It has been thought that inducing labour leads to more C-sections, but a study of over 6,100 women suggests this isn’t the case when induced at 39 weeks
Категории: Biology

Inducing labour at 39 weeks leads to fewer emergency Caesareans

HIV and AIDS - чт, 2018-08-09 00:00
It has been thought that inducing labour leads to more C-sections, but a study of over 6,100 women suggests this isn’t the case when induced at 39 weeks
Категории: Healthcare, Science and society

Inducing labour at 39 weeks leads to fewer emergency Caesareans

Genetically modified organisms (GMO) - чт, 2018-08-09 00:00
It has been thought that inducing labour leads to more C-sections, but a study of over 6,100 women suggests this isn’t the case when induced at 39 weeks
Категории: Science and society

Long-term all-optical interrogation of cortical neurons in awake-behaving nonhuman primates

PLOS Biology (new articles) - ср, 2018-08-08 23:00

by Niansheng Ju, Rundong Jiang, Stephen L. Macknik, Susana Martinez-Conde, Shiming Tang

Whereas optogenetic techniques have proven successful in their ability to manipulate neuronal populations—with high spatial and temporal fidelity—in species ranging from insects to rodents, significant obstacles remain in their application to nonhuman primates (NHPs). Robust optogenetics-activated behavior and long-term monitoring of target neurons have been challenging in NHPs. Here, we present a method for all-optical interrogation (AOI), integrating optical stimulation and simultaneous two-photon (2P) imaging of neuronal populations in the primary visual cortex (V1) of awake rhesus macaques. A red-shifted channel-rhodopsin transgene (ChR1/VChR1 [C1V1]) and genetically encoded calcium indicators (genetically encoded calmodulin protein [GCaMP]5 or GCaMP6s) were delivered by adeno-associated viruses (AAVs) and subsequently expressed in V1 neuronal populations for months. We achieved optogenetic stimulation using both single-photon (1P) activation of neuronal populations and 2P activation of single cells, while simultaneously recording 2P calcium imaging in awake NHPs. Optogenetic manipulations of V1 neuronal populations produced reliable artificial visual percepts. Together, our advances show the feasibility of precise and stable AOI of cortical neurons in awake NHPs, which may lead to broad applications in high-level cognition and preclinical testing studies.
Категории: Biology, Journals

‘Hey’: short messages are the best dating site strategy, study says

Genetics - ср, 2018-08-08 21:00
An analysis of online dating has found most users hit on people who are 25 per cent more attractive than them, and that shorter messages have better reply rates
Категории: Biology

‘Hey’: short messages are the best dating site strategy, study says

HIV and AIDS - ср, 2018-08-08 21:00
An analysis of online dating has found most users hit on people who are 25 per cent more attractive than them, and that shorter messages have better reply rates
Категории: Healthcare, Science and society

‘Hey’: short messages are the best dating site strategy, study says

Genetically modified organisms (GMO) - ср, 2018-08-08 21:00
An analysis of online dating has found most users hit on people who are 25 per cent more attractive than them, and that shorter messages have better reply rates
Категории: Science and society

Police can now track killers using relatives’ DNA – but should they?

Genetics - ср, 2018-08-08 20:00
Genetic genealogy services are rapidly becoming a key source of forensic evidence, but do we really want the police to have access to everyone's DNA?
Категории: Biology

Ecstasy-like drugs might relieve social difficulties in autism

Genetics - ср, 2018-08-08 20:00
Mouse studies hint that social difficulties in autism might be caused by faulty serotonin signalling in the brain and can be helped with serotonin-boosting drugs
Категории: Biology

Police can now track killers using relatives’ DNA – but should they?

HIV and AIDS - ср, 2018-08-08 20:00
Genetic genealogy services are rapidly becoming a key source of forensic evidence, but do we really want the police to have access to everyone's DNA?
Категории: Healthcare, Science and society

Ecstasy-like drugs might relieve social difficulties in autism

HIV and AIDS - ср, 2018-08-08 20:00
Mouse studies hint that social difficulties in autism might be caused by faulty serotonin signalling in the brain and can be helped with serotonin-boosting drugs
Категории: Healthcare, Science and society

Police can now track killers using relatives’ DNA – but should they?

Genetically modified organisms (GMO) - ср, 2018-08-08 20:00
Genetic genealogy services are rapidly becoming a key source of forensic evidence, but do we really want the police to have access to everyone's DNA?
Категории: Science and society

Ecstasy-like drugs might relieve social difficulties in autism

Genetically modified organisms (GMO) - ср, 2018-08-08 20:00
Mouse studies hint that social difficulties in autism might be caused by faulty serotonin signalling in the brain and can be helped with serotonin-boosting drugs
Категории: Science and society

Don’t give up, we can survive even a Hothouse Earth

Genetics - ср, 2018-08-08 19:22
Bad news on the climate should lead neither to despair nor unfounded optimism. Instead, we need to roll up our sleeves and prepare for life on a drastically changing planet
Категории: Biology