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Feedback: What would happen if Earth was made of blueberries?

HIV and AIDS - пт, 2018-08-10 12:00
Thanks to science, we now have an answer. Plus: a stolen shark, mapping the Kessel Run, TripAdvisor reviews of migrating animals, and more
Категории: Healthcare, Science and society

Allergy explosion: What causes allergies and how to avoid them

HIV and AIDS - пт, 2018-08-10 11:00
We've all heard that being too clean can cause allergies, or exposure can help you beat them. Most advice doesn't stand up, but there are things that do seem to work
Категории: Healthcare, Science and society

Allergy explosion: What causes allergies and how to avoid them

Genetics - пт, 2018-08-10 11:00
We've all heard that being too clean can cause allergies, or exposure can help you beat them. Most advice doesn't stand up, but there are things that do seem to work
Категории: Biology

Allergy explosion: What causes allergies and how to avoid them

Genetically modified organisms (GMO) - пт, 2018-08-10 11:00
We've all heard that being too clean can cause allergies, or exposure can help you beat them. Most advice doesn't stand up, but there are things that do seem to work
Категории: Science and society

A systems genetics resource and analysis of sleep regulation in the mouse

PLOS Biology (new articles) - чт, 2018-08-09 23:00

by Shanaz Diessler, Maxime Jan, Yann Emmenegger, Nicolas Guex, Benita Middleton, Debra J. Skene, Mark Ibberson, Frederic Burdet, Lou Götz, Marco Pagni, Martial Sankar, Robin Liechti, Charlotte N. Hor, Ioannis Xenarios, Paul Franken

Sleep is essential for optimal brain functioning and health, but the biological substrates through which sleep delivers these beneficial effects remain largely unknown. We used a systems genetics approach in the BXD genetic reference population (GRP) of mice and assembled a comprehensive experimental knowledge base comprising a deep “sleep-wake” phenome, central and peripheral transcriptomes, and plasma metabolome data, collected under undisturbed baseline conditions and after sleep deprivation (SD). We present analytical tools to interactively interrogate the database, visualize the molecular networks altered by sleep loss, and prioritize candidate genes. We found that a one-time, short disruption of sleep already extensively reshaped the systems genetics landscape by altering 60%–78% of the transcriptomes and the metabolome, with numerous genetic loci affecting the magnitude and direction of change. Systems genetics integrative analyses drawing on all levels of organization imply α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and fatty acid turnover as substrates of the negative effects of insufficient sleep. Our analyses demonstrate that genetic heterogeneity and the effects of insufficient sleep itself on the transcriptome and metabolome are far more widespread than previously reported.
Категории: Biology, Journals

We have measured the speed of death and it’s 2 millimetres an hour

Genetically modified organisms (GMO) - чт, 2018-08-09 21:00
Biologists have watched death spread across a living cell for the first time, and discovered that it travels in a steady wave in the same way that wildfires do
Категории: Science and society

We have measured the speed of death and it’s 2 millimetres an hour

Genetics - чт, 2018-08-09 21:00
Biologists have watched death spread across a living cell for the first time, and discovered that it travels in a steady wave in the same way that wildfires do
Категории: Biology

We have measured the speed of death and it’s 2 millimetres an hour

HIV and AIDS - чт, 2018-08-09 21:00
Biologists have watched death spread across a living cell for the first time, and discovered that it travels in a steady wave in the same way that wildfires do
Категории: Healthcare, Science and society

High-speed electrons prove Einstein was right about the speed of light

Genetically modified organisms (GMO) - чт, 2018-08-09 17:43
Albert Einstein predicted that the speed of light does not change just because you are moving – and now two experiments have shown just how right he was
Категории: Science and society

High-speed electrons prove Einstein was right about the speed of light

Genetics - чт, 2018-08-09 17:43
Albert Einstein predicted that the speed of light does not change just because you are moving – and now two experiments have shown just how right he was
Категории: Biology

High-speed electrons prove Einstein was right about the speed of light

HIV and AIDS - чт, 2018-08-09 17:43
Albert Einstein predicted that the speed of light does not change just because you are moving – and now two experiments have shown just how right he was
Категории: Healthcare, Science and society

Allergy explosion: The truth behind the most common myths

Genetically modified organisms (GMO) - чт, 2018-08-09 17:00
You can grow into and out of allergies your whole life; they come in groups; women are more allergy prone... Wild ideas about allergies abound, but which should you believe?
Категории: Science and society

Alien grass is making California wildfires three times as frequent

Genetically modified organisms (GMO) - чт, 2018-08-09 17:00
Non-native grasses such as cheatgrass are easier to ignite and can spread fires far more quickly than the native ones
Категории: Science and society

Allergy explosion: The truth behind the most common myths

Genetics - чт, 2018-08-09 17:00
You can grow into and out of allergies your whole life; they come in groups; women are more allergy prone... Wild ideas about allergies abound, but which should you believe?
Категории: Biology

Alien grass is making California wildfires three times as frequent

Genetics - чт, 2018-08-09 17:00
Non-native grasses such as cheatgrass are easier to ignite and can spread fires far more quickly than the native ones
Категории: Biology

Allergy explosion: The truth behind the most common myths

HIV and AIDS - чт, 2018-08-09 17:00
You can grow into and out of allergies your whole life; they come in groups; women are more allergy prone... Wild ideas about allergies abound, but which should you believe?
Категории: Healthcare, Science and society

Alien grass is making California wildfires three times as frequent

HIV and AIDS - чт, 2018-08-09 17:00
Non-native grasses such as cheatgrass are easier to ignite and can spread fires far more quickly than the native ones
Категории: Healthcare, Science and society

Uncrackable computer chips stop malicious bugs attacking your computer

Genetically modified organisms (GMO) - чт, 2018-08-09 14:00
Cyberattacks target not just our phones and laptops, but hospitals, schools and power stations. A new security solution redesigns chips from the inside out
Категории: Science and society

Uncrackable computer chips stop malicious bugs attacking your computer

HIV and AIDS - чт, 2018-08-09 14:00
Cyberattacks target not just our phones and laptops, but hospitals, schools and power stations. A new security solution redesigns chips from the inside out
Категории: Healthcare, Science and society

Uncrackable computer chips stop malicious bugs attacking your computer

Genetics - чт, 2018-08-09 14:00
Cyberattacks target not just our phones and laptops, but hospitals, schools and power stations. A new security solution redesigns chips from the inside out
Категории: Biology