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Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

Immunity (most read) - чт, 2013-09-26 02:00
Nu Zhang, Michael J. Bevan. Tissue-resident memory T (Trm) cells represent a population of memory CD8+ T cells that can act as first responders to local infection. The mechanisms regulating the formation and maint....
Категории: Biology, Healthcare, Immunology, Journals

Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases

Molecular Cell (most read) - чт, 2013-09-26 02:00
Dennis Castor, Nidhi Nair, Anne-Cécile Déclais, Christophe Lachaud, Rachel Toth, Thomas J. Macartney, David M.J. Lilley, J.Simon C. Arthur, John Rouse. Holliday junctions (HJs) are X-shaped DNA structures that arise during homologous recombination, which must be removed to enable chromosome segregation. The SLX1 and MUS81-EME1 nucleases can both ....