Prediction of DNA-binding residues in proteins from amino acid sequences using a random forest model with a hybrid feature - Motivation: In this work, we aim to develop a computational approach for predicting DNA-binding sites in proteins from amino acid sequences.
Predicting DNA recognition by Cys2His2 zinc finger proteins - Motivation: Cys2His2 zinc finger (ZF) proteins represent the largest class of eukaryotic transcription factors.
Discovery of phosphorylation motif mixtures in phosphoproteomics data - Motivation: Modification of proteins via phosphorylation is a primary mechanism for signal transduction in cells.
Slider--maximum use of probability information for alignment of short sequence reads and SNP detection - Motivation: A plethora of alignment tools have been created that are designed to best fit different types of alignment conditions.
KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors - Motivation: We noted that the sumoylation site in C/EBP homologues is conserved beyond the canonical consensus sequence for sumoylation.
A novel procedure for genotyping of single nucleotide polymorphisms in trisomy with genomic DNA and the invader assay - Individuals with trisomy 21 display complex phenotypes with differing degrees of severity.
Identification and recovery of minor HIV-1 variants using the heteroduplex tracking assay and biotinylated probes - We describe a method to identify and recover minor human immunodeficiency virus type 1 (HIV-1) sequence variants from a complex population.
Rapid and reliable universal cloning of influenza A virus genes by target-primed plasmid amplification - Reverse genetics has become pivotal in influenza virus research relying on rapid generation of tailored recombinant influenza viruses.
Modeling genetic inheritance of copy number variations - Copy number variations (CNVs) are being used as genetic markers or functional candidates in gene-mapping studies.
Identifying molecular markers associated with classification of genotypes by External Logistic Biplots - For characterization of genetic diversity in genotypes several molecular techniques, usually resulting in a binary data matrix, have been used.