Archive - Aug 2009

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August 8th

Copy number variation has little impact on bead-array-based measures of DNA methylation

Copy number variation has little impact on bead-array-based measures of DNA methylation - Motivation: Integration of various genome-scale measures of molecular alterations is of great interest to researchers aiming to better define disease processes or identify novel targets with clinical utility.

PROMISE: a tool to identify genomic features with specific biological associations with multiple endpoint variables

PROMISE: a tool to identify genomic features with a specific biologically interesting pattern of associations with multiple endpoint variables - Motivation: In some applications, prior biological knowledge can be used to define a specific pattern of association of multiple endpoint variables with a

A statistical framework for protein quantitation in bottom-up MS-based proteomics

A statistical framework for protein quantitation in bottom-up MS-based proteomics - Motivation: Quantitative mass spectrometry-based proteomics requires protein-level estimates and associated confidence measures.