Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles - Expressed polycistronic microRNA (miR) cassettes have useful properties that can be utilized for RNA interference (RNAi)-based gene silencing.
Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships - Transcriptional regulation is mediated by the collective binding of proteins called transcription factors to cis-regulatory elements.