Feed aggregator

The mystery of the dinosaur with crocodile jaws, bear claws and a sail

Genetically modified organisms (GMO) - Thu, 2018-09-20 17:00
No one knows why dinosaurs never conquered the seas. But giant semi-aquatic predator Spinosaurus is revealing some teasing hints
Categories: Science and society

Octopuses taking MDMA get all huggy and loved-up with each other

Genetically modified organisms (GMO) - Thu, 2018-09-20 17:00
Octopuses respond to ecstasy in the same way as we do, suggesting the basis for social behaviour evolved more than 500 million years ago
Categories: Science and society

Animals can count, but can’t read numbers – and now we know why

Genetically modified organisms (GMO) - Thu, 2018-09-20 17:00
Humans but not animals learn that symbols like ‘2’ and ‘4’ represent numbers by recruiting a unique set of neurons to identify them
Categories: Science and society

NASA’s new exoplanet-hunter has spotted its first alien worlds

Genetics - Thu, 2018-09-20 14:25
NASA’s recently launched exoplanet-hunting satellite has uncovered a new world twice the size of Earth orbiting a star 60 light years away
Categories: Biology

NASA’s new exoplanet-hunter has spotted its first alien worlds

HIV and AIDS - Thu, 2018-09-20 14:25
NASA’s recently launched exoplanet-hunting satellite has uncovered a new world twice the size of Earth orbiting a star 60 light years away

NASA’s new exoplanet-hunter has spotted its first alien worlds

Genetically modified organisms (GMO) - Thu, 2018-09-20 14:25
NASA’s recently launched exoplanet-hunting satellite has uncovered a new world twice the size of Earth orbiting a star 60 light years away
Categories: Science and society

A pair of tiny hopping rovers are about to land on an asteroid

Genetics - Thu, 2018-09-20 13:13
Japan’s Hayabusa 2 spacecraft has arrived at the asteroid Ryugu, and now it is dropping off two tiny landers that will hop around the surface and take pictures
Categories: Biology

A pair of tiny hopping rovers are about to land on an asteroid

HIV and AIDS - Thu, 2018-09-20 13:13
Japan’s Hayabusa 2 spacecraft has arrived at the asteroid Ryugu, and now it is dropping off two tiny landers that will hop around the surface and take pictures

A pair of tiny hopping rovers are about to land on an asteroid

Genetically modified organisms (GMO) - Thu, 2018-09-20 13:13
Japan’s Hayabusa 2 spacecraft has arrived at the asteroid Ryugu, and now it is dropping off two tiny landers that will hop around the surface and take pictures
Categories: Science and society

10 mysteries of the universe: How will it all end?

Genetics - Thu, 2018-09-20 12:00
Supernovae are violent stellar explosions that pepper the cosmos. Studying them revealed the enigma of dark energy – a force that will determine the universe's fate
Categories: Biology

10 mysteries of the universe: How will it all end?

Genetically modified organisms (GMO) - Thu, 2018-09-20 12:00
Supernovae are violent stellar explosions that pepper the cosmos. Studying them revealed the enigma of dark energy – a force that will determine the universe's fate
Categories: Science and society

Watch now: Follow the action at New Scientist Live

Genetics - Thu, 2018-09-20 10:30
Follow the action live from the world's biggest festival of ideas and discovery – New Scientist Live, at the ExCeL Centre in London from 20-23 September
Categories: Biology

Watch now: Follow the action at New Scientist Live

Genetically modified organisms (GMO) - Thu, 2018-09-20 10:30
Follow the action live from the world's biggest festival of ideas and discovery – New Scientist Live, at the ExCeL Centre in London from 20-23 September
Categories: Science and society

10 mysteries of the universe: What came before the big bang?

Genetics - Thu, 2018-09-20 10:00
Searing bursts of radio waves first spotted a decade ago could come from bouncing black holes – and that suggests a universe might have existed before ours
Categories: Biology

10 mysteries of the universe: What came before the big bang?

Genetically modified organisms (GMO) - Thu, 2018-09-20 10:00
Searing bursts of radio waves first spotted a decade ago could come from bouncing black holes – and that suggests a universe might have existed before ours
Categories: Science and society

Field notes: Polluted polar bears await the great Arctic land grab

Genetics - Thu, 2018-09-20 08:00
As global warming melts the Arctic, all eyes are turning to the riches under the ice. But will polar bears survive the pollutants trickling into the food chain?
Categories: Biology

Field notes: Polluted polar bears await the great Arctic land grab

HIV and AIDS - Thu, 2018-09-20 08:00
As global warming melts the Arctic, all eyes are turning to the riches under the ice. But will polar bears survive the pollutants trickling into the food chain?

Field notes: Polluted polar bears await the great Arctic land grab

Genetically modified organisms (GMO) - Thu, 2018-09-20 08:00
As global warming melts the Arctic, all eyes are turning to the riches under the ice. But will polar bears survive the pollutants trickling into the food chain?
Categories: Science and society

Correction: Comparative genomics and the nature of placozoan species

PLOS Biology (new articles) - Wed, 2018-09-19 23:00

by Michael Eitel, Warren R. Francis, Frédérique Varoqueaux, Jean Daraspe, Hans-Jürgen Osigus, Stefan Krebs, Sergio Vargas, Helmut Blum, Gray A. Williams, Bernd Schierwater, Gert Wörheide

Categories: Biology, Journals

Anthropoid primate–specific retroviral element THE1B controls expression of <i>CRH</i> in placenta and alters gestation length

PLOS Biology (new articles) - Wed, 2018-09-19 23:00

by Caitlin E. Dunn-Fletcher, Lisa M. Muglia, Mihaela Pavlicev, Gernot Wolf, Ming-An Sun, Yueh-Chiang Hu, Elizabeth Huffman, Shivani Tumukuntala, Katri Thiele, Amrita Mukherjee, Sandra Zoubovsky, Xuzhe Zhang, Kayleigh A. Swaggart, Katherine Y. Bezold Lamm, Helen Jones, Todd S. Macfarlan, Louis J. Muglia

Pregnancy and parturition are intricately regulated to ensure successful reproductive outcomes. However, the factors that control gestational length in humans and other anthropoid primates remain poorly defined. Here, we show the endogenous retroviral long terminal repeat transposon-like human element 1B (THE1B) selectively controls placental expression of corticotropin-releasing hormone (CRH) that, in turn, influences gestational length and birth timing. Placental expression of CRH and subsequently prolonged gestational length were found in two independent strains of transgenic mice carrying a 180-kb human bacterial artificial chromosome (BAC) DNA that contained the full length of CRH and extended flanking regions, including THE1B. Restricted deletion of THE1B silenced placental CRH expression and normalized birth timing in these transgenic lines. Furthermore, we revealed an interaction at the 5′ insertion site of THE1B with distal-less homeobox 3 (DLX3), a transcription factor expressed in placenta. Together, these findings suggest that retroviral insertion of THE1B into the anthropoid primate genome may have initiated expression of CRH in placental syncytiotrophoblasts via DLX3 and that this placental CRH is sufficient to alter the timing of birth.
Categories: Biology, Journals