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A Role for a Dioxygenase in Auxin Metabolism and Reproductive Development in Rice

Developmental Cell (most read) - Thu, 2013-10-03 02:00
Zhigang Zhao, Yunhui Zhang, Xi Liu, Xin Zhang, Shichang Liu, Xiaowen Yu, Yulong Ren, Xiaomin Zheng, Kunneng Zhou, Ling Jiang, Xiuping Guo, Ying Gai, Chuanyin Wu, Huqu Zhai, Haiyang Wang, Jianmin Wan. Indole-3-acetic acid (IAA), the natural auxin in plants, regulates many aspects of plant growth and development. Extensive analyses have elucidated the components of auxin biosynthesis, transport,....
Categories: Biology, Journals

Control of T Helper 2 Responses by Transcription Factor IRF4-Dependent Dendritic Cells

Immunity (most read) - Thu, 2013-09-26 02:00
Yan Gao, Simone A. Nish, Ruoyi Jiang, Lin Hou, Paula Licona-Limón, Jason S. Weinstein, Hongyu Zhao, Ruslan Medzhitov. CD4+ T cell differentiation is regulated by specialized antigen-presenting cells. Dendritic cells (DCs) produce cytokines that promote naive CD4+ T cell differentiation into ....

CD301b+ Dermal Dendritic Cells Drive T Helper 2 Cell-Mediated Immunity

Immunity (most read) - Thu, 2013-09-26 02:00
Yosuke Kumamoto, Melissa Linehan, Jason S. Weinstein, Brian J. Laidlaw, Joseph E. Craft, Akiko Iwasaki. Unlike other types of T helper (Th) responses, whether the development of Th2 cells requires instruction from particular subset of dendritic cells (DCs) remains unclear. By using an in vivo deplet....

Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

Immunity (most read) - Thu, 2013-09-26 02:00
Nu Zhang, Michael J. Bevan. Tissue-resident memory T (Trm) cells represent a population of memory CD8+ T cells that can act as first responders to local infection. The mechanisms regulating the formation and maint....

Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases

Molecular Cell (most read) - Thu, 2013-09-26 02:00
Dennis Castor, Nidhi Nair, Anne-Cécile Déclais, Christophe Lachaud, Rachel Toth, Thomas J. Macartney, David M.J. Lilley, J.Simon C. Arthur, John Rouse. Holliday junctions (HJs) are X-shaped DNA structures that arise during homologous recombination, which must be removed to enable chromosome segregation. The SLX1 and MUS81-EME1 nucleases can both ....