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Nucleic Acids Research

Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples
Site-specific labeling of Saccharomyces cerevisiae ribosomes for single-molecule manipulations
Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression
Titration-free massively parallel pyrosequencing using trace amounts of starting material
A fluorescence-based reporter substrate for monitoring RNA editing in trypanosomatid pathogens

Bioinformatics

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Biology

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair 19 hours 35 min old, Molecular Cell (most read)
A Consensus of Core Protein Complex Compositions for Saccharomyces cerevisiae 19 hours 35 min old, Molecular Cell (most read)
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets 19 hours 35 min old, Molecular Cell (most read)
What the Mitochondria See 19 hours 35 min old, Molecular Cell (most read)
Dephosphorylation of F-BAR Protein Cdc15 Modulates Its Conformation and Stimulates Its Scaffolding Activity at the Cell Division Site 19 hours 35 min old, Molecular Cell (most read)
Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases 19 hours 35 min old, Molecular Cell (most read)
Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing 19 hours 35 min old, Molecular Cell (most read)
The Diversity of Ubiquitin Recognition: Hot Spots and Varied Specificity 19 hours 35 min old, Molecular Cell (most read)
Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface 19 hours 35 min old, Molecular Cell (most read)
Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2 19 hours 35 min old, Molecular Cell (most read)
MicroRNA Biogenesis via Splicing and Exosome-Mediated Trimming in Drosophila 19 hours 35 min old, Molecular Cell (most read)
Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α 19 hours 35 min old, Molecular Cell (most read)
Lysine Methylation Regulates E2F1-Induced Cell Death 19 hours 35 min old, Molecular Cell (most read)
How Many Ways Are There to Generate Small RNAs? 19 hours 35 min old, Molecular Cell (most read)
Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes 19 hours 35 min old, Molecular Cell (most read)

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Science and society

Galapagos: off the danger list, still in danger 8 hours 24 min old, HIV and AIDS
Reptilians were the earliest North American pioneers 9 hours 7 min old, HIV and AIDS
Are cloned steak and milk on European menus? 10 hours 1 min old, HIV and AIDS
Dog brains rotated by selective breeding 10 hours 3 min old, HIV and AIDS
Graphene bubbles mimic explosive magnetic field 10 hours 22 min old, HIV and AIDS
Team-working robots huddle together to boost comms 10 hours 53 min old, HIV and AIDS
Cosmic Trojans may sneak comets towards Earth 13 hours 28 min old, HIV and AIDS
US food waste worth more than offshore drilling 14 hours 34 min old, HIV and AIDS
Regulation could save genome scanning, not kill it 1 day 3 hours old, HIV and AIDS
E. coli engineered to make convenient 'drop-in' biofuel 1 day 6 hours old, HIV and AIDS
Today on New Scientist: 29 July 2010 1 day 7 hours old, HIV and AIDS
Galapagos off the Danger List – but why? 1 day 8 hours old, HIV and AIDS
Satellite quantum communication circles closer 1 day 10 hours old, HIV and AIDS
Phytoplankton in decline: bye bye food chain? 1 day 10 hours old, HIV and AIDS
Inside TRAK: a new robot shows us how we think 1 day 10 hours old, HIV and AIDS

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Healthcare

Galapagos: off the danger list, still in danger 8 hours 24 min old, HIV and AIDS
Reptilians were the earliest North American pioneers 9 hours 7 min old, HIV and AIDS
Are cloned steak and milk on European menus? 10 hours 1 min old, HIV and AIDS
Dog brains rotated by selective breeding 10 hours 3 min old, HIV and AIDS
Graphene bubbles mimic explosive magnetic field 10 hours 22 min old, HIV and AIDS
Team-working robots huddle together to boost comms 10 hours 53 min old, HIV and AIDS
Cosmic Trojans may sneak comets towards Earth 13 hours 28 min old, HIV and AIDS
US food waste worth more than offshore drilling 14 hours 34 min old, HIV and AIDS
T Helper Cell Differentiation: Understanding the Needs of Hierarchy 19 hours 35 min old, Immunity (most read)
MicroRNA-34a Perturbs B Lymphocyte Development by Repressing the Forkhead Box Transcription Factor Foxp1 19 hours 35 min old, Immunity (most read)
Type I Interferons Regulate Cytolytic Activity of Memory CD8+ T Cells in the Lung Airways during Respiratory Virus Challenge 19 hours 35 min old, Immunity (most read)
Maintaining Cell Identity through Global Control of Genomic Organization 19 hours 35 min old, Immunity (most read)
The Sensing of Environmental Stimuli by Follicular Dendritic Cells Promotes Immunoglobulin A Generation in the Gut 19 hours 35 min old, Immunity (most read)
Development and Migration of Plasma Cells in the Mouse Lymph Node 19 hours 35 min old, Immunity (most read)
Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor 19 hours 35 min old, Immunity (most read)

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Journals

Hsc70/Hsp90 Chaperone Machinery Mediates ATP-Dependent RISC Loading of Small RNA Duplexes 19 hours 35 min old, Molecular Cell (most read)
How To Survive and Thrive in the Mother-Mentor Marathon 19 hours 35 min old, Molecular Cell (most read)
How To Choose a Good Scientific Problem 19 hours 35 min old, Molecular Cell (most read)
How Many Ways Are There to Generate Small RNAs? 19 hours 35 min old, Molecular Cell (most read)
Lysine Methylation Regulates E2F1-Induced Cell Death 19 hours 35 min old, Molecular Cell (most read)
Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases 19 hours 35 min old, Molecular Cell (most read)
Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing 19 hours 35 min old, Molecular Cell (most read)
What the Mitochondria See 19 hours 35 min old, Molecular Cell (most read)
Dephosphorylation of F-BAR Protein Cdc15 Modulates Its Conformation and Stimulates Its Scaffolding Activity at the Cell Division Site 19 hours 35 min old, Molecular Cell (most read)
Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia 19 hours 35 min old, Molecular Cell (most read)
Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α 19 hours 35 min old, Molecular Cell (most read)
Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration 19 hours 35 min old, Molecular Cell (most read)
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation 19 hours 35 min old, Molecular Cell (most read)
A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair 19 hours 35 min old, Molecular Cell (most read)
The Diversity of Ubiquitin Recognition: Hot Spots and Varied Specificity 19 hours 35 min old, Molecular Cell (most read)

More

Bioinformatics

Site-specific labeling of Saccharomyces cerevisiae ribosomes for single-molecule manipulations 4 days 6 hours old, Nucleic Acids Research
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples 4 days 6 hours old, Nucleic Acids Research
A rationally designed peptide enhances homologous recombination in vitro and resistance to DNA damaging agents in vivo 4 days 6 hours old, Nucleic Acids Research
Evidence that MEK1 positively promotes interhomologue double-strand break repair 4 days 6 hours old, Nucleic Acids Research
Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae 4 days 6 hours old, Nucleic Acids Research
Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene 4 days 6 hours old, Nucleic Acids Research
Targeting of 5-aza-2'-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme 4 days 6 hours old, Nucleic Acids Research
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing 4 days 6 hours old, Nucleic Acids Research
Quantitative design and experimental validation for a single-molecule DNA nanodevice transformable among three structural states 4 days 6 hours old, Nucleic Acids Research
Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence 4 days 6 hours old, Nucleic Acids Research
Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes 4 days 6 hours old, Nucleic Acids Research
Translation of TRAF1 is regulated by IRES-dependent mechanism and stimulated by vincristine 4 days 6 hours old, Nucleic Acids Research
Arabidopsis thaliana XRN2 is required for primary cleavage in the pre-ribosomal RNA 4 days 6 hours old, Nucleic Acids Research
A dictionary on microRNAs and their putative target pathways 4 days 6 hours old, Nucleic Acids Research
Efficient inhibition of miR-155 function in vivo by peptide nucleic acids 4 days 6 hours old, Nucleic Acids Research

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Molecular and cell biology

Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases 19 hours 35 min old, Molecular Cell (most read)
Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing 19 hours 35 min old, Molecular Cell (most read)
Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α 19 hours 35 min old, Molecular Cell (most read)
A Consensus of Core Protein Complex Compositions for Saccharomyces cerevisiae 19 hours 35 min old, Molecular Cell (most read)
Lysine Methylation Regulates E2F1-Induced Cell Death 19 hours 35 min old, Molecular Cell (most read)
How Many Ways Are There to Generate Small RNAs? 19 hours 35 min old, Molecular Cell (most read)
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation 19 hours 35 min old, Molecular Cell (most read)
MicroRNA Biogenesis via Splicing and Exosome-Mediated Trimming in Drosophila 19 hours 35 min old, Molecular Cell (most read)
Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia 19 hours 35 min old, Molecular Cell (most read)
Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface 19 hours 35 min old, Molecular Cell (most read)
Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration 19 hours 35 min old, Molecular Cell (most read)
A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair 19 hours 35 min old, Molecular Cell (most read)
What the Mitochondria See 19 hours 35 min old, Molecular Cell (most read)
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets 19 hours 35 min old, Molecular Cell (most read)
Dephosphorylation of F-BAR Protein Cdc15 Modulates Its Conformation and Stimulates Its Scaffolding Activity at the Cell Division Site 19 hours 35 min old, Molecular Cell (most read)

More

Immunology

Development and Migration of Plasma Cells in the Mouse Lymph Node 19 hours 35 min old, Immunity (most read)
MicroRNA-34a Perturbs B Lymphocyte Development by Repressing the Forkhead Box Transcription Factor Foxp1 19 hours 35 min old, Immunity (most read)
Type I Interferons Regulate Cytolytic Activity of Memory CD8+ T Cells in the Lung Airways during Respiratory Virus Challenge 19 hours 35 min old, Immunity (most read)
The Sensing of Environmental Stimuli by Follicular Dendritic Cells Promotes Immunoglobulin A Generation in the Gut 19 hours 35 min old, Immunity (most read)
Toll-like Receptor 4 Signaling by Follicular Dendritic Cells Is Pivotal for Germinal Center Onset and Affinity Maturation 19 hours 35 min old, Immunity (most read)
K33-Linked Polyubiquitination of T Cell Receptor-ζ Regulates Proteolysis-Independent T Cell Signaling 19 hours 35 min old, Immunity (most read)
CXCL5 Regulates Chemokine Scavenging and Pulmonary Host Defense to Bacterial Infection 19 hours 35 min old, Immunity (most read)
Maintaining Cell Identity through Global Control of Genomic Organization 19 hours 35 min old, Immunity (most read)
Regulation of MicroRNA Expression and Abundance during Lymphopoiesis 19 hours 35 min old, Immunity (most read)
Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor 19 hours 35 min old, Immunity (most read)
Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways 19 hours 35 min old, Immunity (most read)
Genome-wide Profiling of Interleukin-4 and STAT6 Transcription Factor Regulation of Human Th2 Cell Programming 19 hours 35 min old, Immunity (most read)
Apoptosis Threshold Set by Noxa and Mcl-1 after T Cell Activation Regulates Competitive Selection of High-Affinity Clones 19 hours 35 min old, Immunity (most read)
Interleukin-1β Selectively Expands and Sustains Interleukin-22+ Immature Human Natural Killer Cells in Secondary Lymphoid Tissue 19 hours 35 min old, Immunity (most read)
Intrinsic Properties of immunoglobulin IgG1 Isotype-Switched B Cell Receptors Promote Microclustering and the Initiation of Signaling 19 hours 35 min old, Immunity (most read)

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Chemistry

Probing Translation with Small-Molecule Inhibitors 1 day 19 hours old, Chemistry and Biology (most read)
In Vivo Imaging with a Cell-Permeable Porphyrin-Based MRI Contrast Agent 1 day 19 hours old, Chemistry and Biology (most read)
Special Issue ITI 1 day 19 hours old, Chemistry and Biology (most read)
Bridging the Gaps between Synapses, Circuits, and Behavior 1 day 19 hours old, Chemistry and Biology (most read)
Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms 1 day 19 hours old, Chemistry and Biology (most read)
Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor 1 day 19 hours old, Chemistry and Biology (most read)
Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition 1 day 19 hours old, Chemistry and Biology (most read)
Protein Chemical Modification on Endogenous Amino Acids 1 day 19 hours old, Chemistry and Biology (most read)
Quantitative Cell-Based Reporter Gene Assays Using Droplet-Based Microfluidics 1 day 19 hours old, Chemistry and Biology (most read)
Five Molecules We Would Take to a Remote Island 1 day 19 hours old, Chemistry and Biology (most read)
Biochemical Target Isolation for Novices: Affinity-Based Strategies 1 day 19 hours old, Chemistry and Biology (most read)
Targeting the Undruggable Proteome: The Small Molecules of My Dreams 1 day 19 hours old, Chemistry and Biology (most read)
Emergence of Chemical Biology Approaches to the RNAi/miRNA Pathway 1 day 19 hours old, Chemistry and Biology (most read)
Probing the Probes: Fitness Factors For Small Molecule Tools 1 day 19 hours old, Chemistry and Biology (most read)
Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology 1 day 19 hours old, Chemistry and Biology (most read)

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Stem Cells

An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity 2 days 19 hours old, Stem Cell: most read
Epigenetic Priming of a Pre-B Cell-Specific Enhancer through Binding of Sox2 and Foxd3 at the ESC Stage 2 days 19 hours old, Stem Cell: most read
Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins 2 days 19 hours old, Stem Cell: most read
Keeping Them Quiet: BMPs Maintain Adult Neural Stem Cell Quiescence 2 days 19 hours old, Stem Cell: most read
Tumor Oncogenotypes and Lung Cancer Stem Cell Identity 2 days 19 hours old, Stem Cell: most read
A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal 2 days 19 hours old, Stem Cell: most read
A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells 2 days 19 hours old, Stem Cell: most read
A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts 2 days 19 hours old, Stem Cell: most read
Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming 2 days 19 hours old, Stem Cell: most read
When Fibroblasts MET iPSCs 2 days 19 hours old, Stem Cell: most read
Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells 2 days 19 hours old, Stem Cell: most read
Patient-Specific Pluripotent Stem Cells Become Even More Accessible 2 days 19 hours old, Stem Cell: most read
Patients Beware: Commercialized Stem Cell Treatments on the Web 2 days 19 hours old, Stem Cell: most read
Generation of Induced Pluripotent Stem Cells from Human Terminally Differentiated Circulating T Cells 2 days 19 hours old, Stem Cell: most read
Reprogramming of T Cells from Human Peripheral Blood 2 days 19 hours old, Stem Cell: most read

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Cancer

Wnt/Ca2+/NFAT Signaling Maintains Survival of Ph+ Leukemia Cells upon Inhibition of Bcr-Abl 2 weeks 3 days old, Cancer Cell
A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma 2 weeks 3 days old, Cancer Cell
PCBP1 Suppresses the Translation of Metastasis-Associated PRL-3 Phosphatase 2 weeks 3 days old, Cancer Cell
Integrative Genomic Profiling of Human Prostate Cancer 2 weeks 3 days old, Cancer Cell
4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors 2 weeks 3 days old, Cancer Cell
PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3 2 weeks 3 days old, Cancer Cell
Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors 2 weeks 3 days old, Cancer Cell
Testimony from the Bedside: From Coley's Toxins to Targeted Immunotherapy 2 weeks 3 days old, Cancer Cell
The Molecular Biology of Myeloproliferative Disorders 2 weeks 3 days old, Cancer Cell
All Roads Lead to the Ribosome 2 weeks 3 days old, Cancer Cell
HIF-1α Partners with FoxA2, a Neuroendocrine-Specific Transcription Factor, to Promote Tumorigenesis 2 weeks 3 days old, Cancer Cell
New Views into the Prostate Cancer Genome 2 weeks 3 days old, Cancer Cell
ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading 5 weeks 21 hours old, Cancer Cell
The PAF Complex Synergizes with MLL Fusion Proteins at HOX Loci to Promote Leukemogenesis 5 weeks 21 hours old, Cancer Cell
GSK-3 Promotes Conditional Association of CREB and Its Coactivators with MEIS1 to Facilitate HOX-Mediated Transcription and Oncogenesis 5 weeks 21 hours old, Cancer Cell

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