Visualization of the protein-coding regions with a self adaptive spectral rotation approach

Visualization of the protein-coding regions with a self adaptive spectral rotation approach - Identifying protein-coding regions in DNA sequences is an active issue in computational biology.

Automated construction and testing of multi-locus gene-gene associations

Automated construction and testing of multi-locus gene-gene associations - Summary: It has been argued that the missing heritability in common diseases may be in part due to rare variants and gene–gene effects.

Statistical confidence measures for genome maps: application to the validation of genome assemblies

Statistical confidence measures for genome maps: application to the validation of genome assemblies - Motivation: Genome maps are imperative to address the genetic basis of the biology of an organism.

Advanced computational algorithms for microbial community analysis using massive 16S rRNA sequence data

Advanced computational algorithms for microbial community analysis using massive 16S rRNA sequence data - With the aid of next-generation sequencing technology, researchers can now obtain millions of microbial signature sequences for diverse applications ranging from human epidemiological studies to global ocean surv

Optimizing the noise versus bias trade-off for Illumina whole genome expression BeadChips

Optimizing the noise versus bias trade-off for Illumina whole genome expression BeadChips - Five strategies for pre-processing intensities from Illumina expression BeadChips are assessed from the point of view of precision and bias.

High-quality annotation of promoter regions for 913 bacterial genomes

High-quality annotation of promoter regions for 913 bacterial genomes - Motivation: The number of bacterial genomes being sequenced is increasing very rapidly and hence, it is crucial to have procedures for rapid and reliable annotation of their functional elements such as promoter regions, which co

PyETV: a PyMOL evolutionary trace viewer to analyze functional site predictions in protein complexes

PyETV: a PyMOL evolutionary trace viewer to analyze functional site predictions in protein complexes - Summary: PyETV is a PyMOL plugin for viewing, analyzing and manipulating predictions of evolutionarily important residues and sites in protein structures and their complexes.

Pre-calculated protein structure alignments at the RCSB PDB website

Pre-calculated protein structure alignments at the RCSB PDB website - Summary: With the continuous growth of the RCSB Protein Data Bank (PDB), providing an up-to-date systematic structure comparison of all protein structures poses an ever growing challenge.

The SMARTCyp cytochrome P450 metabolism prediction server

The SMARTCyp cytochrome P450 metabolism prediction server - Summary: The SMARTCyp server is the first web application for site of metabolism prediction of cytochrome P450-mediated drug metabolism.

R/qtl: high-throughput multiple QTL mapping

R/qtl: high-throughput multiple QTL mapping - Motivation: R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of experimental cross types.